Heterogeneity among Mycobacterium ulcerans isolates from Africa.

Publication Type:Journal Article
Year of Publication:2006
Authors:P. Stragier, Ablordey, A., L Bayonne, M., Lugor, Y. L., Sindani, I. S., Suykerbuyk, P., Wabinga, H., Meyers, W. M., Portaels, F.
Journal:Emerg Infect Dis
Volume:12
Issue:5
Pagination:844-7
Date Published:2006 May
ISSN:1080-6040
Keywords:Africa, Bacterial Typing Techniques, Base Sequence, Genetic Variation, Genotype, Humans, Molecular Epidemiology, Molecular Sequence Data, Mycobacterium Infections, Nontuberculous, Mycobacterium ulcerans, Phylogeny, Polymorphism, Genetic, Tandem Repeat Sequences
Abstract:

Mycobacterium ulcerans causes Buruli ulcer, an ulcerative skin disease in tropical and subtropical areas. Despite restricted genetic diversity, mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis on M. ulcerans revealed 3 genotypes from different African countries. It is the first time this typing method succeeded directly on patient samples.

DOI:10.3201/eid1205.051191
Alternate Journal:Emerging Infect. Dis.
Scratchpads developed and conceived by (alphabetical): Ed Baker, Katherine Bouton Alice Heaton Dimitris Koureas, Laurence Livermore, Dave Roberts, Simon Rycroft, Ben Scott, Vince Smith