Publication Type: | Journal Article |
Year of Publication: | 2005 |
Authors: | A. Ablordey, Hilty, M., Stragier, P., Swings, J., Portaels, F. |
Journal: | J Clin Microbiol |
Volume: | 43 |
Issue: | 10 |
Pagination: | 5281-4 |
Date Published: | 2005 Oct |
ISSN: | 0095-1137 |
Keywords: | Bacterial Typing Techniques, Base Sequence, Genetic Variation, Genotype, Humans, Minisatellite Repeats, Molecular Sequence Data, Mycobacterium ulcerans, Polymorphism, Genetic, Sequence Alignment, Species Specificity |
Abstract: | We analyzed a set of variable-number tandem-repeat (VNTR) loci to assess their nucleotide sequence diversity in isolates of three Mycobacterium ulcerans genotypes. Sequence variants in two loci resulted in intraspecies resolution of Southeast Asian and Asian genotypes in contrast to a homogenous sequence composition among African isolates. Nucleotide sequence polymorphism in repeat units can enhance discrimination of VNTR loci. |
DOI: | 10.1128/JCM.43.10.5281-5284.2005 |
Alternate Journal: | J. Clin. Microbiol. |